Now we have architected Microsoft Discovery to be extremely extensible, enabling researchers to combine the newest Microsoft improvements with their very own fashions, instruments, and datasets in addition to a variety of companion and open-source options.
We’re saying a brand new enterprise agentic platform referred to as Microsoft Discovery to speed up analysis and growth (R&D) at Microsoft Construct 2025.
Our aim is to carry the ability of AI to scientists and engineers to rework your entire discovery course of—from superior information reasoning and speculation formulation to experimental simulation and iterative studying. Microsoft Discovery permits researchers to collaborate with a staff of specialised AI brokers mixed with a graph-based information engine, to drive scientific outcomes with velocity, scale, and accuracy.
Now we have architected Microsoft Discovery to be extremely extensible, enabling researchers to combine the newest Microsoft improvements with their very own fashions, instruments, and datasets in addition to a variety of companion and open-source options. Constructed on prime of Microsoft Azure, belief, compliance, transparency, and governance are key design rules of this enterprise-ready platform to allow accountable innovation, retaining the researcher in management.
At Microsoft, our researchers have leveraged the superior AI fashions and high-performance computing (HPC) simulation instruments in Microsoft Discovery to find a novel coolant prototype with promising properties for immersion cooling in datacenters in about 200 hours—a course of that in any other case would have taken months, if not years. This speedy discovery lays the groundwork for future developments in safer and sustainable options throughout a number of industries and is an indication of how Microsoft Discovery can doubtlessly remodel R&D in any firm.
We’re working with a notable set of Microsoft clients who’re fascinated by co-innovating in numerous industries together with chemistry and supplies, silicon design, vitality, manufacturing, and pharma. We’re additionally working with a broad companion base that’s constructing on prime of the platform to drive this acceleration, and we couldn’t be extra excited. The probabilities are infinite as we understand the total potential of AI in R&D and we’re simply getting began!
The agentic imaginative and prescient for science
At Microsoft, we need to amplify the ingenuity of scientists to usher in a brand new period of accelerating discovery and develop the horizons of analysis. Doing so requires empowering R&D groups with transformative applied sciences that may drive significant enterprise impression. Nevertheless, R&D has very particular challenges in comparison with different domains:
- Scientific information is huge, nuanced, and distributed.
- The invention course of is numerous and dynamic, involving a number of extremely specialised strategies and duties, making it very laborious to attach the dots throughout the totally different domains concerned.
- R&D is iterative. There are hardly ever easy, clear-cut solutions. As an alternative, scientific information evolves by means of proof, discourse, and refinement.
This complexity calls for a brand new paradigm—one which isn’t aimed toward doing the identical experiments quicker, however relatively basically altering the paradigm of how we method R&D.
Think about if each researcher may collaborate with a tireless staff of clever, synergistic AI brokers with the only objective of accelerated innovation. That is our imaginative and prescient for a brand new agentic R&D paradigm, embedding AI in each stage of the scientific technique.
On this new world, folks and specialised AI brokers will cooperatively refine information and experimentation in actual time in a steady, iterative cycle of discovery—all whereas sustaining the management, transparency, and belief that enterprises and governmental establishments require. This requires a complete platform the place AI can seize each the scientific area and the cognitive processes concerned in managing scientific thought. To appreciate this imaginative and prescient, scientific AI brokers should be capable of:
- Motive over a fancy and contextual graph connecting all information sources.
- Specialize throughout distinct domains and duties.
- Study from outcomes and adapt whole analysis plans accordingly.
Introducing Microsoft Discovery
We’re taking a giant step towards realizing this imaginative and prescient with Microsoft Discovery, bringing agentic R&D to life by leveraging the newest improvements from Microsoft and the broader scientific ecosystem.
Graph-based scientific co-reasoning
The arrival of enormous language fashions (LLMs) hinted at this new period, providing capabilities to hurry up sure scientific duties, significantly for data retrieval and speculation technology. Nevertheless, LLMs usually lack the contextual understanding required to deeply cause over distributed, nuanced, and infrequently contradictory scientific knowledge.
Microsoft Discovery is constructed on prime of a robust graph-based information engine. As an alternative of merely retrieving info, this engine builds graphs of nuanced relationships between proprietary knowledge in addition to exterior scientific analysis. This permits the platform to have a deep understanding of conflicting theories, numerous experimental outcomes, and even underlying assumptions throughout disciplines.
This contextual reasoning can also be clear. Fairly than outputting monolithic solutions, it retains the knowledgeable within the loop with detailed supply monitoring and reasoning, offering the extent of transparency in AI programs that builds belief, ensures accountability, and permits specialists to validate and perceive each step or make any changes as wanted.
Specialised discovery brokers for conducting analysis
As an alternative of siloed and static pipelines, Microsoft Discovery implements a steady and iterative R&D cycle the place researchers can information and orchestrate a staff of specialised AI brokers that be taught and adapt over time—not only for reasoning, however for conducting analysis itself. The definition of those specialised brokers captures each area information and course of logic, merely by means of pure language.
R&D groups will be capable of construct a customized AI staff aligned to their particular processes and information, simply encoding these brokers with their experience and methodologies to make sure they’ll adapt and orchestrate as analysis progresses. This method is much extra versatile than hard-coding behaviors of at the moment’s digital simulation instruments, which frequently are extremely specialised and lack streamlined integration with others, and it signifies that analysis groups not require computational experience to drive impression. For example, customers can entry and outline varied brokers’ specialties, equivalent to ‘molecular properties simulation specialist’ or ‘literature evaluation specialist.’ They’ll even recommend which instruments or fashions the brokers ought to use or create, and the way they need to collaborate with others.
This natural, bidirectional collaboration is a game-changer for managing R&D: brokers are usually not solely able to working for the researchers, however with them in a fashion that may really amplify human ingenuity—seeing each the forest and the timber without delay.
On the heart of this collaboration is Microsoft Copilot, appearing as a scientific AI assistant that orchestrates these specialised brokers based mostly on the researcher’s prompts. Copilot is conscious of all of the instruments, fashions, and information bases in a buyer’s catalog on the platform, can establish which brokers to leverage, and might arrange end-to-end workflows that cowl the total discovery course of by combining superior AI and HPC simulations by means of the joint work of those brokers.
Extensible and enterprise-ready
Microsoft Discovery is constructed on prime of Azure infrastructure and providers, leveraging by design the belief, compliance, and governance controls on the core of Microsoft’s safe cloud basis.
We imagine within the energy of an open ecosystem that leverages the strengths of Microsoft’s newest developments together with different modern options from clients and companions. Microsoft Discovery permits R&D groups to increase the platform’s catalog by bringing their toolkit of option to cowl their particular analysis wants in a complete scientific bookshelf. This extensibility on the core of Microsoft Discovery simplifies the onboarding of their alternative of computational instruments, fashions, and information bases—whether or not they’re customized developments, open-source, or industrial options. As we carry to market new capabilities in dependable quantum computing and embodied AI, the platform will stay future-proofed with the very best applied sciences obtainable at Microsoft and throughout the business.
Actual impression: Discovering a novel, non-PFAS coolant prototype
Over the previous months, we’ve got made vital strides aiding computational scientists of their analysis and incorporating cutting-edge improvements from Microsoft Analysis. This has led to outstanding breakthroughs, equivalent to discovering a novel solid-state electrolyte candidate that makes use of 70% much less lithium in collaboration with the Division of Power’s Pacific Northwest Nationwide Laboratory (PNNL) and enabling speedy computational simulations that speed up scientific discoveries at Unilever. Microsoft Discovery is designed to carry these improvements to each scientist—not solely these with deep computational experience.
One of many extra thrilling early use circumstances of Microsoft Discovery is unfolding on the Pacific Northwest Nationwide Laboratory, the place scientists are utilizing Microsoft Discovery’s superior generative AI and HPC capabilities to additional develop machine studying fashions that predict and optimize complicated chemical separations—a important course of in nuclear science. These separations are important for successfully isolating radioactive parts after the nuclear fission course of, a notoriously time-sensitive and extremely chemically complicated activity. Sooner or later, the staff goals to make use of these developments to scale back the time scientists should spend in hazardous radioactive environments, whereas bettering yields and purity, enhancing each security and effectivity.
—Scott Godwin, Director, Middle for Cloud Computing, Pacific Northwest Nationwide Laboratory
By leveraging superior AI fashions and HPC instruments for simulation that will probably be obtainable on Microsoft Discovery, Microsoft researchers found a novel, non-PFAS, immersion datacenter coolant prototype in about 200 hours.1 Present coolants usually take a few years to develop and might comprise dangerous PFAS-based chemical compounds that make them unviable to make use of, as there’s a worldwide push to ban these “ceaselessly chemical compounds” in favor of extra environmentally pleasant choices on this business and lots of others.
After the digital discovery course of, we efficiently synthesized this coolant prototype in below 4 months, and it’s at present below additional evaluation and refinement. Now we have already examined among the main properties of this materials and so they align to the AI predictions, which is a testomony to the accuracy of the predictive fashions used. Whereas this mission is just an experiment, it lays the groundwork for future developments and enhancements in coolant know-how and demonstrates how the mix of HPC and specialised AI fashions can speed up and remodel R&D processes.
Based on Daniel Pope, founding father of Submer, an organization whose mission is to construct datacenters with a robust give attention to sustainability, effectivity, and a better utilization of assets:
The velocity and depth of molecular screening achieved by Microsoft Discovery would’ve been unimaginable with conventional strategies. What as soon as took years of lab work and trial and error, Microsoft Discovery can accomplish in simply weeks, and with higher confidence.
A rising ecosystem
We’re placing this enterprise-grade platform into the fingers of worldwide innovators to display real-world impression throughout industries—from chemistry and pharma to manufacturing and silicon design.
It’s solely with a robust ecosystem that we’ll be capable of understand the total potential of Microsoft Discovery, and it’s why we’re working with clients, companions, and different Microsoft groups to carry first-party developments along with main business instruments and area experience.
Prospects and inner collaborators
GSK is working to revolutionize healthcare, uniting science, know-how and expertise—together with world-class partnerships—to get forward of illness collectively. The corporate makes use of tech to advance science and speed up the event and supply of medicines and vaccines to positively impression the well being of individuals at scale.
GSK’s depth and breadth of information and built-in use of tech throughout each a part of its enterprise—from early scientific exploration by means of to fabricate and supply of medicines and vaccines in market—present a novel providing when working with others. The corporate appears ahead to a potential partnership with Microsoft with the intent of additional advancing GSK’s generative platforms for parallel prediction and testing, creating new medicines with higher velocity and precision, and doubtlessly remodeling medicinal chemistry to new unimaginable ranges. The probabilities forward are thrilling, and collectively, we are able to attempt for probably the most modern options for sufferers and for well being.
The Estée Lauder Corporations has gained a worldwide repute for high-quality skincare, make-up, haircare and perfume merchandise that ship extremely efficient outcomes demonstrated by intensive analysis and product analysis. The corporate is worked up to harness the ability of Microsoft Discovery to additional speed up the event of merchandise that uphold the best requirements of excellence.
Our proprietary R&D knowledge, stemming from the minds of our sensible scientists and almost 80 years of analysis, growth, and experimentation, is a key aggressive benefit. The Microsoft Discovery platform will assist us to unleash the ability of our knowledge to drive quick, agile, breakthrough innovation and high-quality, customized merchandise that can delight our customers.
—Kosmas Kretsos, PhD, MBA, Vice President, R&D and Innovation Know-how, The Estée Lauder Corporations
Moreover, Microsoft is releasing a medical analysis agent that makes use of the identical graph-based information engine obtainable in Microsoft Discovery to reinforce data retrieval by synthesizing insights from trusted medical journals. As a part of a broader set of specialised brokers within the healthcare agent orchestrator code pattern in Azure AI Foundry, this agent permits researchers and builders to ship actionable and evidence-based steering tailor-made particularly to complicated, multi-disciplinary healthcare workflows—equivalent to most cancers care.
Area-specific choices
Combining Microsoft’s and NVIDIA’s strengths in generative Al and scientific computing, we plan to combine Microsoft Discovery with NVIDIA ALCHEMI and NVIDIA BioNeMo NIM microservices to speed up breakthroughs in supplies and life sciences. Supplies researchers will now have entry to state-of-the-art inference capabilities for candidate identification, property mapping, and artificial knowledge technology. Biomolecular R&D groups will be capable of speed up Al mannequin growth for drug discovery, leveraging pre-trained BioNeMo Al workflows, all in Microsoft Discovery’s unified, enterprise-grade platform.
Researchers may deploy their AI brokers on high-performance NVIDIA-accelerated Azure AI Foundry infrastructure, enabling them to effectively course of and synthesize giant volumes of scientific knowledge with distinctive velocity and responsiveness for accelerated discovery and enhanced analysis outcomes.
AI is dramatically accelerating the tempo of scientific discovery. By integrating NVIDIA ALCHEMI and BioNeMo NIM microservices into Azure Discovery, we’re giving scientists the flexibility to maneuver from knowledge to discovery with unprecedented velocity, scale, and effectivity.
—Dion Harris, Senior Director of Accelerated Information Middle Options, NVIDIA
Moreover, we plan to combine Synopsys’ business options in Microsoft Discovery to speed up semiconductor engineering, serving to each {hardware} designers and software program builders ship superior merchandise.
Semiconductor engineering is among the many most complicated, consequential, and high-stakes scientific endeavors of our time, which makes it an especially compelling use case for synthetic intelligence. By integrating Synopsys’ pioneering AI-powered design options with Microsoft Discovery, we are able to understand the potential of agentic AI, re-engineer chip design workflows, supercharge engineering productiveness, and speed up the tempo of know-how innovation.
—Raja Tabet, Senior Vice President, Engineering Excellence Group, Synopsys
Microsoft can also be working with PhysicsX, planning to combine the corporate’s physics AI basis fashions into Microsoft Discovery so clients can unlock new ranges of automation, optimization, and efficiency throughout engineering and manufacturing.
The Microsoft Discovery platform represents a seismic shift in how AI can speed up scientific discovery and engineering. That is about remodeling how complicated bodily programs are designed, constructed, and operated throughout superior industries—in aerospace and protection, semiconductors, minerals and supplies, vitality, and automotive. Collectively, PhysicsX and Microsoft are constructing the software program infrastructure that can outline the following period of engineering.
—Jacomo Corbo, Chief Govt Officer and Cofounder, PhysicsX
Integration help
Lastly, we’re excited to companion with a rising checklist of software program integrators, equivalent to Accenture and Capgemini, to assist clients and collaborators scale customized platform deployments.
Along with Microsoft, we’re shaping a daring AI imaginative and prescient for organizations who use deep science to carry modern merchandise to sufferers and customers. Our laboratory transformation methods and Microsoft’s Microsoft Discovery platform create a dynamic ecosystem for scientific development. This collaboration will assist us understand the laboratory of the longer term, enabling scientists to push the boundaries of discovery, experimentation, and testing with higher velocity and precision.
—Adam Borenstein, Managing Director, International Laboratory Reinvention Lead, Accenture
We’re excited to be bringing the Microsoft Discovery platform and AI brokers to R&D-intensive sectors. We imagine these applied sciences have the potential to allow knowledgeable scientists to unlock step adjustments within the tempo of innovation, bringing transformative advantages to enterprise and society. This partnership will drive productiveness in laboratory-driven R&D by drawing on Capgemini’s business expertise, specialist bodily and organic AI capabilities, and science-led ‘lab-in-the-loop’ mental property, together with that of Cambridge Consultants, the deep tech powerhouse of Capgemini. For our shoppers this might imply accelerated discovery and predictive modelling or different aggressive benefits by means of utilizing knowledge and AI at scale.
—Roshan Gya, Chief Govt Officer, Capgemini Invent
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Study extra about how Microsoft Discovery may help scientists and engineers remodel analysis and growth:
¹Based on the definitions of PFAS supplied by the Organisation for Financial Co-operation and Growth (OECD) (2021), the U.S. Environmental Safety Company and Buck et. al. (2011)
